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Cardiotrophin-1 promotes cardiomyocyte differentiation from mouse induced pluripotent stem cells via JAK2/STAT3/Pim-1 signaling pathway

BACKGROUND: The induced pluripotent stem cell (iPSC) has shown great potential in cellular therapy of myocardial infarction (MI), while its application is hampered by the low efficiency of cardiomyocyte differentiation. The present study was designed to investigate the effects of cardiotrophin-1 (CT...

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Detalles Bibliográficos
Autores principales: Liu, Tong, Zhang, Ran, Guo, Tao, Ma, Sai, Han, Dong, Li, Xiu-Juan, Jin, Yan, Fan, Miao-Miao, Wang, Ya-Bin, Chen, Yun-Dai, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712363/
https://www.ncbi.nlm.nih.gov/pubmed/26788034
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.06.002