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Reduced β-cell function in early preclinical type 1 diabetes

OBJECTIVE: We aimed to characterize insulin responses to i.v. glucose during the preclinical period of type 1 diabetes starting from the emergence of islet autoimmunity. DESIGN AND METHODS: A large population-based cohort of children with HLA-conferred susceptibility to type 1 diabetes was observed...

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Detalles Bibliográficos
Autores principales: Koskinen, Maarit K, Helminen, Olli, Matomäki, Jaakko, Aspholm, Susanna, Mykkänen, Juha, Mäkinen, Marjaana, Simell, Ville, Vähä-Mäkilä, Mari, Simell, Tuula, Ilonen, Jorma, Knip, Mikael, Veijola, Riitta, Toppari, Jorma, Simell, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712442/
https://www.ncbi.nlm.nih.gov/pubmed/26620391
http://dx.doi.org/10.1530/EJE-15-0674