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Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells

BACKGROUND: Open reading frames are common in long noncoding RNAs (lncRNAs) and 5’UTRs of protein coding transcripts (uORFs). The question of whether those ORFs are translated was recently addressed by several groups using ribosome profiling. Most of those studies concluded that certain lncRNAs and...

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Detalles Bibliográficos
Autores principales: Popa, Alexandra, Lebrigand, Kevin, Barbry, Pascal, Waldmann, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712605/
https://www.ncbi.nlm.nih.gov/pubmed/26764022
http://dx.doi.org/10.1186/s12864-016-2384-0