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Association of polymorphisms with a family history of cancer and the presence of germline mutations in the BRCA1/BRCA2 genes

INTRODUCTION: Breast cancer (BC) is an important public health problem worldwide. In Brazil, breast cancer is the most frequently diagnosed tumor and the leading cause of cancer death in women. Hereditary cancer represents approximately 5 to 10 % of BC cases. Even outside the hereditary cancer conte...

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Detalles Bibliográficos
Autores principales: Fernandes, Gabriela C., Michelli, Rodrigo A. D., Scapulatempo-Neto, Cristovam, Palmero, Edenir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712611/
https://www.ncbi.nlm.nih.gov/pubmed/26770289
http://dx.doi.org/10.1186/s13053-015-0042-1