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Double-stranded microRNA mimics can induce length- and passenger strand–dependent effects in a cell type–specific manner

MicroRNAs are short (17–26) noncoding RNAs driving or modulating physiological and pathological cellular events. Overexpression of miR-155 is pathogenic in B-cell malignancy but was also reported in a number of solid tumors—in particular, in breast cancer, where its role remains unclear and often co...

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Detalles Bibliográficos
Autores principales: Goldgraben, Mae A., Russell, Roslin, Rueda, Oscar M., Caldas, Carlos, Git, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712670/
https://www.ncbi.nlm.nih.gov/pubmed/26670622
http://dx.doi.org/10.1261/rna.054072.115