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Multiple protein–protein interactions converging on the Prp38 protein during activation of the human spliceosome

Spliceosomal Prp38 proteins contain a conserved amino-terminal domain, but only higher eukaryotic orthologs also harbor a carboxy-terminal RS domain, a hallmark of splicing regulatory SR proteins. We show by crystal structure analysis that the amino-terminal domain of human Prp38 is organized around...

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Detalles Bibliográficos
Autores principales:	Schütze, Tonio, Ulrich, Alexander K.C., Apelt, Luise, Will, Cindy L., Bartlick, Natascha, Seeger, Martin, Weber, Gert, Lührmann, Reinhard, Stelzl, Ulrich, Wahl, Markus C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712676/ https://www.ncbi.nlm.nih.gov/pubmed/26673105 http://dx.doi.org/10.1261/rna.054296.115

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