Chemical footprinting reveals conformational changes of 18S and 28S rRNAs at different steps of translation termination on the human ribosome

Translation termination in eukaryotes is mediated by release factors: eRF1, which is responsible for stop codon recognition and peptidyl-tRNA hydrolysis, and GTPase eRF3, which stimulates peptide release. Here, we have utilized ribose-specific probes to investigate accessibility of rRNA backbone in...

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Detalles Bibliográficos
Autores principales: Bulygin, Konstantin N., Bartuli, Yulia S., Malygin, Alexey A., Graifer, Dmitri M., Frolova, Ludmila Yu., Karpova, Galina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712677/
https://www.ncbi.nlm.nih.gov/pubmed/26655225
http://dx.doi.org/10.1261/rna.053801.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712677/
https://www.ncbi.nlm.nih.gov/pubmed/26655225
http://dx.doi.org/10.1261/rna.053801.115

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