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Chemical footprinting reveals conformational changes of 18S and 28S rRNAs at different steps of translation termination on the human ribosome

Translation termination in eukaryotes is mediated by release factors: eRF1, which is responsible for stop codon recognition and peptidyl-tRNA hydrolysis, and GTPase eRF3, which stimulates peptide release. Here, we have utilized ribose-specific probes to investigate accessibility of rRNA backbone in...

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Detalles Bibliográficos
Autores principales:	Bulygin, Konstantin N., Bartuli, Yulia S., Malygin, Alexey A., Graifer, Dmitri M., Frolova, Ludmila Yu., Karpova, Galina G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712677/ https://www.ncbi.nlm.nih.gov/pubmed/26655225 http://dx.doi.org/10.1261/rna.053801.115

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