Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease

Both type 1 and type 2 diabetes are associated with altered lipid metabolism, which might in part contribute to debilitating complications such as diabetic kidney disease (DKD). Ceramides are bioactive sphingolipids that have been implicated in a variety of diseases as they can regulate cellular res...

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Detalles Bibliográficos
Autores principales: Sas, Kelli M, Nair, Viji, Byun, Jaeman, Kayampilly, Pradeep, Zhang, Hongyu, Saha, Jharna, Brosius, Frank C, Kretzler, Matthias, Pennathur, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712744/
https://www.ncbi.nlm.nih.gov/pubmed/26778897
http://dx.doi.org/10.4172/jpb.S14-002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712744/
https://www.ncbi.nlm.nih.gov/pubmed/26778897
http://dx.doi.org/10.4172/jpb.S14-002

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