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Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences
High-throughput sequencing of cDNA (RNA-seq) is used extensively to characterize the transcriptome of cells. Many transcriptomic studies aim at comparing either abundance levels or the transcriptome composition between given conditions, and as a first step, the sequencing reads must be used as the b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712774/ https://www.ncbi.nlm.nih.gov/pubmed/26925227 http://dx.doi.org/10.12688/f1000research.7563.2 |