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Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1

Changes in cell morphology require coordination of plasma membrane turnover and cytoskeleton dynamics, processes that are regulated by Rho GTPases. Here, we describe how a direct interaction between the Rho GTPase Cdc42 and the GTPase-activating protein (GAP) GRAF1 (also known as ARHGAP26), facilita...

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Detalles Bibliográficos
Autores principales: Francis, Monika K., Holst, Mikkel R., Vidal-Quadras, Maite, Henriksson, Sara, Santarella-Mellwig, Rachel, Sandblad, Linda, Lundmark, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712783/
https://www.ncbi.nlm.nih.gov/pubmed/26446261
http://dx.doi.org/10.1242/jcs.174417