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Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1
Changes in cell morphology require coordination of plasma membrane turnover and cytoskeleton dynamics, processes that are regulated by Rho GTPases. Here, we describe how a direct interaction between the Rho GTPase Cdc42 and the GTPase-activating protein (GAP) GRAF1 (also known as ARHGAP26), facilita...
Autores principales: | Francis, Monika K., Holst, Mikkel R., Vidal-Quadras, Maite, Henriksson, Sara, Santarella-Mellwig, Rachel, Sandblad, Linda, Lundmark, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712783/ https://www.ncbi.nlm.nih.gov/pubmed/26446261 http://dx.doi.org/10.1242/jcs.174417 |
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