Neuregulin-1-mediated ErbB2–ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation

During placentation, foetal trophoblasts invade deeply into maternal tissue to establish a foeto–maternal circulation. We have previously shown that extravillous trophoblast (EVT) lineage cells express ErbB2 and ErbB3, of which the potential as an oncogenic unit is well established. However, a physi...

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Detalles Bibliográficos
Autores principales: Fock, Valerie, Plessl, Kerstin, Draxler, Peter, Otti, Gerlinde Regina, Fiala, Christian, Knöfler, Martin, Pollheimer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712818/
https://www.ncbi.nlm.nih.gov/pubmed/26490994
http://dx.doi.org/10.1242/jcs.176933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712818/
https://www.ncbi.nlm.nih.gov/pubmed/26490994
http://dx.doi.org/10.1242/jcs.176933

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