Sqstm1–GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells

Sqstm1 serves as a signaling hub and receptor for selective autophagy. Consequently, dysregulation of Sqstm1 causes imbalances in signaling pathways and disrupts proteostasis, thereby contributing to the development of human diseases. Environmental stresses influence the level of Sqstm1 by altering...

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Detalles Bibliográficos
Autores principales: Eino, Atsushi, Kageyama, Shun, Uemura, Takefumi, Annoh, Hiromichi, Saito, Tetsuya, Narita, Ichiei, Waguri, Satoshi, Komatsu, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Tools and Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712822/
https://www.ncbi.nlm.nih.gov/pubmed/26483381
http://dx.doi.org/10.1242/jcs.180174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712822/
https://www.ncbi.nlm.nih.gov/pubmed/26483381
http://dx.doi.org/10.1242/jcs.180174

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