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Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

Test batteries to screen chemicals for mutagenic hazard include several endpoints regarded as effective for detecting genotoxic carcinogens. Traditional in vivo methods primarily examine clastogenic endpoints in haematopoietic tissues. Although this approach is effective for identifying systemically...

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Detalles Bibliográficos
Autores principales: Long, Alexandra S., Lemieux, Christine L., Arlt, Volker M., White, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712826/
https://www.ncbi.nlm.nih.gov/pubmed/26603514
http://dx.doi.org/10.1016/j.taap.2015.11.010