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Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma

Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiation. When this process is disrupted, retinoblastoma, a developmental tumor of the retina, can form. Epigenetic modulators are central to precisely coordi...

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Detalles Bibliográficos
Autores principales: Aldiri, Issam, Ajioka, Itsuki, Xu, Beisi, Zhang, Jiakun, Chen, Xiang, Benavente, Claudia, Finkelstein, David, Johnson, Dianna, Akiyama, Jennifer, Pennacchio, Len A., Dyer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712833/
https://www.ncbi.nlm.nih.gov/pubmed/26628093
http://dx.doi.org/10.1242/dev.124800