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Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma
Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiation. When this process is disrupted, retinoblastoma, a developmental tumor of the retina, can form. Epigenetic modulators are central to precisely coordi...
Autores principales: | Aldiri, Issam, Ajioka, Itsuki, Xu, Beisi, Zhang, Jiakun, Chen, Xiang, Benavente, Claudia, Finkelstein, David, Johnson, Dianna, Akiyama, Jennifer, Pennacchio, Len A., Dyer, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712833/ https://www.ncbi.nlm.nih.gov/pubmed/26628093 http://dx.doi.org/10.1242/dev.124800 |
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