ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm

The secreted glycoprotein sonic hedgehog (Shh) is expressed in the prechordal mesoderm, where it plays a crucial role in induction and patterning of the ventral forebrain. Currently little is known about how Shh is regulated in prechordal tissue. Here we show that in the embryonic chick, Shh is expr...

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Detalles Bibliográficos
Autores principales: Ellis, Pamela S., Burbridge, Sarah, Soubes, Sandrine, Ohyama, Kyoji, Ben-Haim, Nadav, Chen, Canhe, Dale, Kim, Shen, Michael M., Constam, Daniel, Placzek, Marysia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712875/
https://www.ncbi.nlm.nih.gov/pubmed/26417042
http://dx.doi.org/10.1242/dev.119628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712875/
https://www.ncbi.nlm.nih.gov/pubmed/26417042
http://dx.doi.org/10.1242/dev.119628

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