Structural forms of the human amylase locus and their relationships to SNPs, haplotypes, and obesity

Hundreds of genes reside in structurally complex, poorly understood regions of the human genome(1-3). One such region contains the three amylase genes (AMY2B, AMY2A, and AMY1) responsible for digesting starch into sugar. The copy number of AMY1 is reported to be the genome’s largest influence on obe...

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Detalles Bibliográficos
Autores principales: Usher, Christina L, Handsaker, Robert E, Esko, Tõnu, Tuke, Marcus A, Weedon, Michael N, Hastie, Alex R, Cao, Han, Moon, Jennifer E, Kashin, Seva, Fuchsberger, Christian, Metspalu, Andres, Pato, Carlos N, Pato, Michele T, McCarthy, Mark I, Boehnke, Michael, Altshuler, David M, Frayling, Timothy M, Hirschhorn, Joel N, McCarroll, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712930/
https://www.ncbi.nlm.nih.gov/pubmed/26098870
http://dx.doi.org/10.1038/ng.3340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712930/
https://www.ncbi.nlm.nih.gov/pubmed/26098870
http://dx.doi.org/10.1038/ng.3340

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