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Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration

Postnatal tissue quiescence is thought to be a default state in the absence of a proliferative stimulus such as injury. Previous studies have demonstrated that certain embryonic development programs are reactivated aberrantly in adult organs to drive repair and regeneration(1–3), it is not well unde...

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Detalles Bibliográficos
Autores principales: Peng, Tien, Frank, David B., Kadzik, Rachel S., Morley, Michael P., Rathi, Komal S., Wang, Tao, Zhou, Su, Cheng, Lan, Lu, Min Min, Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713039/
https://www.ncbi.nlm.nih.gov/pubmed/26436454
http://dx.doi.org/10.1038/nature14984