Analysis of a four generation family reveals the widespread sequence-dependent maintenance of allelic DNA methylation in somatic and germ cells

Differential methylation of the homologous chromosomes, a well-known mechanism leading to genomic imprinting and X-chromosome inactivation, is widely reported at the non-imprinted regions on autosomes. To evaluate the transgenerational DNA methylation patterns in human, we analyzed the DNA methylome...

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Detalles Bibliográficos
Autores principales: Tang, Aifa, Huang, Yi, Li, Zesong, Wan, Shengqing, Mou, Lisha, Yin, Guangliang, Li, Ning, Xie, Jun, Xia, Yudong, Li, Xianxin, Luo, Liya, Zhang, Junwen, Chen, Shen, Wu, Song, Sun, Jihua, Sun, Xiaojuan, Jiang, Zhimao, Chen, Jing, Li, Yingrui, Wang, Jian, Wang, Jun, Cai, Zhiming, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713049/
https://www.ncbi.nlm.nih.gov/pubmed/26758766
http://dx.doi.org/10.1038/srep19260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713049/
https://www.ncbi.nlm.nih.gov/pubmed/26758766
http://dx.doi.org/10.1038/srep19260

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