Cargando…

PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation

The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and RNA polymerase II (PolII) elongation. Here, we provide the first genome-wide profiles for the distribution of the entire complex in mammalian cells using chromatin immunoprecipitation and high through...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yan, Li, Wencheng, Hoque, Mainul, Hou, Liming, Shen, Steven, Tian, Bin, Dynlacht, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713055/
https://www.ncbi.nlm.nih.gov/pubmed/26765774
http://dx.doi.org/10.1371/journal.pgen.1005794