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PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation
The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and RNA polymerase II (PolII) elongation. Here, we provide the first genome-wide profiles for the distribution of the entire complex in mammalian cells using chromatin immunoprecipitation and high through...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713055/ https://www.ncbi.nlm.nih.gov/pubmed/26765774 http://dx.doi.org/10.1371/journal.pgen.1005794 |