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Role of Prolactin Receptors in Lymphangioleiomyomatosis

Pulmonary lymphangioleiomyomatosis (LAM) is a rare lung disease caused by mutations in the tumor suppressor genes encoding Tuberous Sclerosis Complex (TSC) 1 and TSC2. The protein product of the TSC2 gene is a well-known suppressor of the mTOR pathway. Emerging evidence suggests that the pituitary h...

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Detalles Bibliográficos
Autores principales: Alkharusi, Amira, Lesma, Elena, Ancona, Silvia, Chiaramonte, Eloisa, Nyström, Thomas, Gorio, Alfredo, Norstedt, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713116/
https://www.ncbi.nlm.nih.gov/pubmed/26765535
http://dx.doi.org/10.1371/journal.pone.0146653