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Integration of linear and dendritic actin nucleation in Nck-induced actin comets

The Nck adaptor protein recruits cytosolic effectors such as N-WASP that induce localized actin polymerization. Experimental aggregation of Nck SH3 domains at the membrane induces actin comet tails—dynamic, elongated filamentous actin structures similar to those that drive the movement of microbial...

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Detalles Bibliográficos
Autores principales: Borinskaya, Sofya, Velle, Katrina B., Campellone, Kenneth G., Talman, Arthur, Alvarez, Diego, Agaisse, Hervé, Wu, Yi I., Loew, Leslie M., Mayer, Bruce J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713129/
https://www.ncbi.nlm.nih.gov/pubmed/26609071
http://dx.doi.org/10.1091/mbc.E14-11-1555