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Integration of linear and dendritic actin nucleation in Nck-induced actin comets
The Nck adaptor protein recruits cytosolic effectors such as N-WASP that induce localized actin polymerization. Experimental aggregation of Nck SH3 domains at the membrane induces actin comet tails—dynamic, elongated filamentous actin structures similar to those that drive the movement of microbial...
Autores principales: | Borinskaya, Sofya, Velle, Katrina B., Campellone, Kenneth G., Talman, Arthur, Alvarez, Diego, Agaisse, Hervé, Wu, Yi I., Loew, Leslie M., Mayer, Bruce J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713129/ https://www.ncbi.nlm.nih.gov/pubmed/26609071 http://dx.doi.org/10.1091/mbc.E14-11-1555 |
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