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Arl13b and the exocyst interact synergistically in ciliogenesis

Arl13b belongs to the ADP-ribosylation factor family within the Ras superfamily of regulatory GTPases. Mutations in Arl13b cause Joubert syndrome, which is characterized by congenital cerebellar ataxia, hypotonia, oculomotor apraxia, and mental retardation. Arl13b is highly enriched in cilia and is...

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Detalles Bibliográficos
Autores principales: Seixas, Cecília, Choi, Soo Young, Polgar, Noemi, Umberger, Nicole L., East, Michael P., Zuo, Xiaofeng, Moreiras, Hugo, Ghossoub, Rania, Benmerah, Alexandre, Kahn, Richard A., Fogelgren, Ben, Caspary, Tamara, Lipschutz, Joshua H., Barral, Duarte C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713133/
https://www.ncbi.nlm.nih.gov/pubmed/26582389
http://dx.doi.org/10.1091/mbc.E15-02-0061