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Arl13b and the exocyst interact synergistically in ciliogenesis
Arl13b belongs to the ADP-ribosylation factor family within the Ras superfamily of regulatory GTPases. Mutations in Arl13b cause Joubert syndrome, which is characterized by congenital cerebellar ataxia, hypotonia, oculomotor apraxia, and mental retardation. Arl13b is highly enriched in cilia and is...
Autores principales: | Seixas, Cecília, Choi, Soo Young, Polgar, Noemi, Umberger, Nicole L., East, Michael P., Zuo, Xiaofeng, Moreiras, Hugo, Ghossoub, Rania, Benmerah, Alexandre, Kahn, Richard A., Fogelgren, Ben, Caspary, Tamara, Lipschutz, Joshua H., Barral, Duarte C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713133/ https://www.ncbi.nlm.nih.gov/pubmed/26582389 http://dx.doi.org/10.1091/mbc.E15-02-0061 |
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