mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells

Macrophages and dendritic cells exposed to lipopolysaccharide (LPS) convert their lysosomes from small, punctate organelles into a network of tubules. Tubular lysosomes have been implicated in phagosome maturation, retention of fluid phase, and antigen presentation. There is a growing appreciation t...

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Detalles Bibliográficos
Autores principales: Saric, Amra, Hipolito, Victoria E. B., Kay, Jason G., Canton, Johnathan, Antonescu, Costin N., Botelho, Roberto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713134/
https://www.ncbi.nlm.nih.gov/pubmed/26582390
http://dx.doi.org/10.1091/mbc.E15-05-0272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713134/
https://www.ncbi.nlm.nih.gov/pubmed/26582390
http://dx.doi.org/10.1091/mbc.E15-05-0272

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