Cargando…
mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells
Macrophages and dendritic cells exposed to lipopolysaccharide (LPS) convert their lysosomes from small, punctate organelles into a network of tubules. Tubular lysosomes have been implicated in phagosome maturation, retention of fluid phase, and antigen presentation. There is a growing appreciation t...
Autores principales: | Saric, Amra, Hipolito, Victoria E. B., Kay, Jason G., Canton, Johnathan, Antonescu, Costin N., Botelho, Roberto J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713134/ https://www.ncbi.nlm.nih.gov/pubmed/26582390 http://dx.doi.org/10.1091/mbc.E15-05-0272 |
Ejemplares similares
-
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
por: Hipolito, Victoria E. B., et al.
Publicado: (2019) -
mTOR and lysosome regulation
por: Puertollano, Rosa
Publicado: (2014) -
The mTOR–lysosome axis at the centre of ageing
por: Carosi, Julian M., et al.
Publicado: (2021) -
Autophagy termination and lysosome reformation regulated by mTOR
por: Yu, Li, et al.
Publicado: (2010) -
Activity-independent targeting of mTOR to lysosomes in primary osteoclasts
por: Wang, Andrew, et al.
Publicado: (2017)