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Incomplete proteasomal degradation of green fluorescent proteins in the context of tandem fluorescent protein timers

Tandem fluorescent protein timers (tFTs) report on protein age through time-dependent change in color, which can be exploited to study protein turnover and trafficking. Each tFT, composed of two fluorescent proteins (FPs) that differ in maturation kinetics, is suited to follow protein dynamics withi...

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Detalles Bibliográficos
Autores principales: Khmelinskii, Anton, Meurer, Matthias, Ho, Chi-Ting, Besenbeck, Birgit, Füller, Julia, Lemberg, Marius K., Bukau, Bernd, Mogk, Axel, Knop, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713137/
https://www.ncbi.nlm.nih.gov/pubmed/26609072
http://dx.doi.org/10.1091/mbc.E15-07-0525