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Chromatin binding of RCC1 during mitosis is important for its nuclear localization in interphase

RCC1, a guanine nucleotide exchange factor of the small GTPase Ran, plays various roles throughout the cell cycle. However, the functions of RCC1 in biological processes in vivo are still unclear. In particular, although RCC1 has multifunctional domains, the biological significance of each domain is...

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Detalles Bibliográficos
Autores principales: Furuta, Maiko, Hori, Tetsuya, Fukagawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713138/
https://www.ncbi.nlm.nih.gov/pubmed/26564799
http://dx.doi.org/10.1091/mbc.E15-07-0497