Dynamic relocation of the TORC1–Gtr1/2–Ego1/2/3 complex is regulated by Gtr1 and Gtr2

TORC1 regulates cellular growth, metabolism, and autophagy by integrating various signals, including nutrient availability, through the small GTPases RagA/B/C/D in mammals and Gtr1/2 in budding yeast. Rag/Gtr is anchored to the lysosomal/vacuolar membrane by the scaffold protein complex Ragulator/Eg...

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Detalles Bibliográficos
Autores principales: Kira, Shintaro, Kumano, Yuri, Ukai, Hirofumi, Takeda, Eigo, Matsuura, Akira, Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713139/
https://www.ncbi.nlm.nih.gov/pubmed/26609069
http://dx.doi.org/10.1091/mbc.E15-07-0470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713139/
https://www.ncbi.nlm.nih.gov/pubmed/26609069
http://dx.doi.org/10.1091/mbc.E15-07-0470

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