Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation

For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid residues replaceable with cysteine. By replacing each amino acid of the 157 chicken variable region framework residues (FR, 82 residues on V(H) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713166/
https://www.ncbi.nlm.nih.gov/pubmed/26764487
http://dx.doi.org/10.1371/journal.pone.0146907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713166/
https://www.ncbi.nlm.nih.gov/pubmed/26764487
http://dx.doi.org/10.1371/journal.pone.0146907

Ejemplares similares