Cargando…

Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation

For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid residues replaceable with cysteine. By replacing each amino acid of the 157 chicken variable region framework residues (FR, 82 residues on V(H) an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713166/ https://www.ncbi.nlm.nih.gov/pubmed/26764487 http://dx.doi.org/10.1371/journal.pone.0146907

Ejemplares similares

Directed evolution of human scFvs in DT40 cells
por: Lim, Alfred W.Y., et al.
Publicado: (2016)

Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1
por: Rukkawattanakul, Thunchanok, et al.
Publicado: (2017)

Identification of Highly Specific scFvs against Total Adiponectin for Diagnostic Purposes
por: Wilton, Peter, et al.
Publicado: (2017)

A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm
por: Philibert, Pascal, et al.
Publicado: (2007)

ScFvs as Allosteric Inhibitors of VEGFR-2: Novel Tools to Harness VEGF Signaling
por: Ballmer-Hofer, Kurt, et al.
Publicado: (2018)

A Generic Procedure for the Isolation of pH- and Magnesium-Responsive Chicken scFvs for Downstream Purification of Human Antibodies
por: Hinz, Steffen C., et al.
Publicado: (2020)

Antibodies on demand: a fast method for the production of human scFvs with minimal amounts of antigen
por: Babel, Ingrid, et al.
Publicado: (2011)

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain
por: Szykowska, Aleksandra, et al.
Publicado: (2021)

Selection of Anti-Sulfadimidine Specific ScFvs from a Hybridoma Cell by Eukaryotic Ribosome Display
por: Qi, Yonghua, et al.
Publicado: (2009)

Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes
por: Goodwin, Marshall S., et al.
Publicado: (2021)

AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy
por: Ising, Christina, et al.
Publicado: (2017)

Serotype- and serogroup-specific detection of African horsesickness virus using phage displayed chicken scFvs for indirect double antibody sandwich ELISAs
por: van Wyngaardt, Wouter, et al.
Publicado: (2013)

Generation of human scFvs antibodies recognizing a prion protein epitope expressed on the surface of human lymphoblastoid cells
por: Flego, Michela, et al.
Publicado: (2007)

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery
por: Fennell, Brian J, et al.
Publicado: (2013)

Characterization of Anti-Citrinin Specific ScFvs Selected from Non-Immunized Mouse Splenocytes by Eukaryotic Ribosome Display
por: Cheng, Haiwei, et al.
Publicado: (2015)

Correction: AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy
por: Ising, Christina, et al.
Publicado: (2017)

A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs
por: Kellmann, Sarah-Jane, et al.
Publicado: (2017)

Human Monoclonal scFvs that Neutralize Fribrinogenolytic Activity of Kaouthiagin, a Zinc-Metalloproteinase in Cobra (Naja kaouthia) Venom
por: Khanongnoi, Jirawat, et al.
Publicado: (2018)

Production and expression of recombinant anti-V3 scFvs from HIV-1 clade C infected Indian patient
por: Kumar, Rajesh, et al.
Publicado: (2012)

A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C
por: Kumar, Rajesh, et al.
Publicado: (2012)

Generation and functional analysis of single chain variable fragments (scFvs) targeting the nucleocapsid protein of Porcine epidemic diarrhea virus
por: Wang, Fengqing, et al.
Publicado: (2022)

Construction of site selected phage library and characterization of anti-V3 scFvs from Indian clade C HIV-1 infected patient
por: Kumar, R, et al.
Publicado: (2012)

The Intracellular Delivery Of Anti-HPV16 E7 scFvs Through Engineered Extracellular Vesicles Inhibits The Proliferation Of HPV-Infected Cells
por: Ferrantelli, Flavia, et al.
Publicado: (2019)

High-volume hybridoma sequencing on the NeuroMabSeq platform enables efficient generation of recombinant monoclonal antibodies and scFvs for neuroscience research
por: Mitchell, Keith G., et al.
Publicado: (2023)

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain
por: Avril, Arnaud, et al.
Publicado: (2015)

NeuroMabSeq: high volume acquisition, processing, and curation of hybridoma sequences and their use in generating recombinant monoclonal antibodies and scFvs for neuroscience research
por: Mitchell, Keith G., et al.
Publicado: (2023)

Generation and characterization of human monoclonal single chain variable fragments (scFvs) against envelope third variable region (V3) of HIV-1 clade C
por: Kumar, Rajesh, et al.
Publicado: (2012)

A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies
por: Moore, Brenda D., et al.
Publicado: (2023)

Cross-neutralizing anti-HIV-1 human single chain variable fragments(scFvs) against CD4 binding site and N332 glycan identified from a recombinant phage library
por: Khan, Lubina, et al.
Publicado: (2017)

The Versatility of Framework Regions of Chicken V(H) and V(L) to Mutations
por: Shin, Jung Won, et al.
Publicado: (2018)

In vitro and in vivo application of anti-cotinine antibody and cotinine-conjugated compounds
por: Kim, Hyori, et al.
Publicado: (2014)

An anti-EGFR × cotinine bispecific antibody complexed with cotinine-conjugated duocarmycin inhibits growth of EGFR-positive cancer cells with KRAS mutations
por: Jin, Junyeong, et al.
Publicado: (2018)

Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library
por: Yang, Wonjun, et al.
Publicado: (2017)

Is it time to stand united? Fish Veterinary Society (FVS)
por: Mascolo, Dario
Publicado: (2020)

Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues
por: Zhou, Qun, et al.
Publicado: (2021)

In Vitro and In Vivo Evaluation of Cysteine and Site Specific Conjugated Herceptin Antibody-Drug Conjugates
por: Jackson, Dowdy, et al.
Publicado: (2014)

Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation
por: Nilchan, Napon, et al.
Publicado: (2019)

A phosphorylation pattern-recognizing antibody specifically reacts to RNA polymerase II bound to exons
por: Han, Jungwon, et al.
Publicado: (2016)

Clinical Applications of Phage-Derived sFvs and sFv Fusion Proteins
por: Chester, K. A., et al.
Publicado: (2000)

Anaesthesia of laboratory, aquaculture and ornamental fish: Proceedings of the first LASA-FVS Symposium
por: Schroeder, Paul, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k63phiqvb774bkukf9stv6iga9