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Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI
BACKGROUND: As model system, a solid-tumor patient-derived xenograft (PDX) model characterized by high peptide receptor expression and histological tissue homogeneity was used to study radiopeptide targeting. In this solid-tumor model, high tumor uptake of targeting peptides was expected. However, i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713394/ https://www.ncbi.nlm.nih.gov/pubmed/26769345 http://dx.doi.org/10.1186/s13550-016-0160-4 |