Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI

BACKGROUND: As model system, a solid-tumor patient-derived xenograft (PDX) model characterized by high peptide receptor expression and histological tissue homogeneity was used to study radiopeptide targeting. In this solid-tumor model, high tumor uptake of targeting peptides was expected. However, i...

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Detalles Bibliográficos
Autores principales: Haeck, J. C., Bol, K., de Ridder, C. M. A., Brunel, L., Fehrentz, J. A., Martinez, J., van Weerden, W. M., Bernsen, M. R., de Jong, M., Veenland, J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713394/
https://www.ncbi.nlm.nih.gov/pubmed/26769345
http://dx.doi.org/10.1186/s13550-016-0160-4

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