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Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae
Ceramide is synthesized in yeast by two redundant acyl-CoA dependent synthases, Lag1 and Lac1. In lag1∆ lac1∆ cells, free fatty acids and sphingoid bases are elevated, and ceramides are produced through the redundant alkaline ceramidases Ypc1 and Ydc1, working backwards. Even with all four of these...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713442/ https://www.ncbi.nlm.nih.gov/pubmed/26752183 http://dx.doi.org/10.1371/journal.pone.0145831 |