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Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae

Ceramide is synthesized in yeast by two redundant acyl-CoA dependent synthases, Lag1 and Lac1. In lag1∆ lac1∆ cells, free fatty acids and sphingoid bases are elevated, and ceramides are produced through the redundant alkaline ceramidases Ypc1 and Ydc1, working backwards. Even with all four of these...

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Detalles Bibliográficos
Autores principales:	Mallela, Shamroop K., Almeida, Reinaldo, Ejsing, Christer S., Conzelmann, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713442/ https://www.ncbi.nlm.nih.gov/pubmed/26752183 http://dx.doi.org/10.1371/journal.pone.0145831

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