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Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex

p300, a ubiquitous transcription coactivator, plays an important role in gene activation. Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. In this study, we investigated the fun...

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Detalles Bibliográficos
Autores principales: Guo, Zhong, Zheng, Liang, Liao, Xinghua, Geller, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713468/
https://www.ncbi.nlm.nih.gov/pubmed/26751080
http://dx.doi.org/10.1371/journal.pone.0146640