Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease

To successfully treat Alzheimer’s disease (AD), pathophysiological events in preclinical stages need to be identified. Preclinical AD refers to the stages that exhibit amyloid deposition in the brain but have normal cognitive function, which are replicated in young adult APPswe/PS1deltaE9 (deltaE9)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Chengyu, Shi, Yuan, Ohli, Jasmin, Schüller, Ulrich, Dorostkar, Mario M., Herms, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713725/
https://www.ncbi.nlm.nih.gov/pubmed/26724934
http://dx.doi.org/10.1007/s00401-015-1527-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713725/
https://www.ncbi.nlm.nih.gov/pubmed/26724934
http://dx.doi.org/10.1007/s00401-015-1527-8

Ejemplares similares