Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

Wnt/β-catenin activation in adult epidermis can induce new hair follicle formation and tumor development. We used lineage tracing to uncover the relative contribution of different stem cell populations. LGR6(+) and LRIG1(+) stem cells contributed to ectopic hair follicles formed in the sebaceous gla...

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Detalles Bibliográficos
Autores principales: Kretzschmar, Kai, Weber, Christine, Driskell, Ryan R., Calonje, Eduardo, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713864/
https://www.ncbi.nlm.nih.gov/pubmed/26771241
http://dx.doi.org/10.1016/j.celrep.2015.12.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713864/
https://www.ncbi.nlm.nih.gov/pubmed/26771241
http://dx.doi.org/10.1016/j.celrep.2015.12.041

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