Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions

We characterized DNA methylation quantitative trait loci (mQTLs) in a large collection (n=166) of human fetal brain samples spanning 56–166 days post-conception, identifying >16,000 fetal brain mQTLs. Fetal brain mQTLs are primarily cis-acting, enriched in regulatory chromatin domains and transcr...

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Detalles Bibliográficos
Autores principales: Hannon, Eilis, Spiers, Helen, Viana, Joana, Pidsley, Ruth, Burrage, Joe, Murphy, Therese M, Troakes, Claire, Turecki, Gustavo, O’Donovan, Michael C., Schalkwyk, Leonard C., Bray, Nicholas J., Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714325/
https://www.ncbi.nlm.nih.gov/pubmed/26619357
http://dx.doi.org/10.1038/nn.4182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714325/
https://www.ncbi.nlm.nih.gov/pubmed/26619357
http://dx.doi.org/10.1038/nn.4182

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