Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ

BACKGROUND & AIMS: Hepatic stellate cells (HSCs) play a key role in liver fibrosis in various chronic liver disorders including nonalcoholic fatty liver disease (NAFLD). The development of liver fibrosis requires a phenotypic switch from quiescent to activated HSCs. The trigger for HSC activatio...

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Detalles Bibliográficos
Autores principales: Povero, Davide, Panera, Nadia, Eguchi, Akiko, Johnson, Casey D., Papouchado, Bettina G., de Araujo Horcel, Lucas, Pinatel, Eva M., Alisi, Anna, Nobili, Valerio, Feldstein, Ariel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714359/
https://www.ncbi.nlm.nih.gov/pubmed/26783552
http://dx.doi.org/10.1016/j.jcmgh.2015.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714359/
https://www.ncbi.nlm.nih.gov/pubmed/26783552
http://dx.doi.org/10.1016/j.jcmgh.2015.07.007

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