Novel treatment of severe combined immunodeficiency utilizing ex-vivo T-cell depleted haploidentical hematopoietic stem cell transplantation and CD45RA+ depleted donor lymphocyte infusions

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment available for severe combined immunodeficiency (SCID); although, there is a high incidence of severe infections and an increased risk of graft-versus host-disease (GvHD) with HSCT. Early intervention...

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Detalles Bibliográficos
Autores principales: Brodszki, Nicholas, Turkiewicz, Dominik, Toporski, Jacek, Truedsson, Lennart, Dykes, Josefina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714422/
https://www.ncbi.nlm.nih.gov/pubmed/26768987
http://dx.doi.org/10.1186/s13023-016-0385-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714422/
https://www.ncbi.nlm.nih.gov/pubmed/26768987
http://dx.doi.org/10.1186/s13023-016-0385-3

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