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BRCA1 founder mutations do not contribute to increased risk of gastric cancer in the Polish population

BACKGROUND: Gastric cancer (GC) is part of the spectrum of diseases linked to BRCA1 and BRCA2 mutations that increase the risk of breast and ovarian cancer. Data suggesting an increased risk of developing GC among BRCA1 and BRCA2 mutation carriers are based almost exclusively on indirect studies. Th...

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Detalles Bibliográficos
Autores principales: Ławniczak, Małgorzata, Jakubowska, Anna, Białek, Andrzej, Lubiński, Jan, Jaworska–Bieniek, Katarzyna, Kaczmarek, Katarzyna, Starzyńska, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714446/
https://www.ncbi.nlm.nih.gov/pubmed/26779294
http://dx.doi.org/10.1186/s13053-015-0043-0