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Identification and spontaneous immune targeting of an endogenous retrovirus K envelope protein in the Indian rhesus macaque model of human disease
BACKGROUND: Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections that have invaded the germ line of both humans and non-human primates. Most ERVs are functionally crippled by deletions, mutations, and hypermethylation, leading to the view that they are inert genomic fossils....
Autores principales: | Wu, Helen L., Léon, Enrique J., Wallace, Lyle T., Nimiyongskul, Francesca A., Buechler, Matthew B., Newman, Laura P., Castrovinci, Philip A., Paul Johnson, R., Gifford, Robert J., Brad Jones, R., Sacha, Jonah B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714462/ https://www.ncbi.nlm.nih.gov/pubmed/26767784 http://dx.doi.org/10.1186/s12977-016-0238-0 |
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