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Effect of bone morphogenetic protein-4 on in vitro growth, steroidogenesis and subsequent developmental competence of the oocyte-granulosa cell complex derived from bovine early antral follicles

BACKGROUND: Bone morphogenetic proteins (BMPs) play important regulatory roles during folliculogenesis. Theca-derived BMP-4 may be beneficial to in vitro growth culture of early antral follicle-derived oocyte-granulosa cell complexes (OGCs), which is lacking in theca-derived products. METHODS: BMP-4...

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Detalles Bibliográficos
Autores principales: Yang, Yinghua, Kanno, Chihiro, Huang, Weiping, Kang, Sung-Sik, Yanagawa, Yojiro, Nagano, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714481/
https://www.ncbi.nlm.nih.gov/pubmed/26769429
http://dx.doi.org/10.1186/s12958-016-0137-1