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A transgenerational role of the germline nuclear RNAi pathway in repressing heat stress-induced transcriptional activation in C. elegans

BACKGROUND: Environmental stress-induced transgenerational epigenetic effects have been observed in various model organisms and human. The capacity and mechanism of such phenomena are poorly understood. In C. elegans, siRNA mediates transgenerational gene silencing through the germline nuclear RNAi...

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Detalles Bibliográficos
Autores principales: Ni, Julie Zhouli, Kalinava, Natallia, Chen, Esteban, Huang, Alex, Trinh, Thi, Gu, Sam Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714518/
https://www.ncbi.nlm.nih.gov/pubmed/26779286
http://dx.doi.org/10.1186/s13072-016-0052-x