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A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers

BACKGROUND: Explosive synaptogenesis and synaptic pruning occur in the hippocampus during the first two weeks of postnatal life, coincident with a heightened susceptibility to seizures in rodents. To determine the temporal correlation between microglial development and age‐dependent susceptibility a...

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Detalles Bibliográficos
Autores principales: Kim, Iris, Mlsna, Lauren M., Yoon, Stella, Le, Brandy, Yu, Songtao, Xu, Dan, Koh, Sookyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714636/
https://www.ncbi.nlm.nih.gov/pubmed/26807334
http://dx.doi.org/10.1002/brb3.403