Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer

Mammalian target of rapamycin (mTOR) is a serine–threonine kinase that acts downstream of the phosphatidylinositol 3‐kinase signaling pathway and regulates a wide range of cellular functions including transcription, translation, proliferation, apoptosis, and autophagy. Whereas genetic alterations th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaguchi, Hiroyuki, Kawazu, Masahito, Yasuda, Takahiko, Soda, Manabu, Ueno, Toshihide, Kojima, Shinya, Yashiro, Masakazu, Yoshino, Ichiro, Ishikawa, Yuichi, Sai, Eirin, Mano, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714661/
https://www.ncbi.nlm.nih.gov/pubmed/26432419
http://dx.doi.org/10.1111/cas.12828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714661/
https://www.ncbi.nlm.nih.gov/pubmed/26432419
http://dx.doi.org/10.1111/cas.12828

Ejemplares similares